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Neuropharmacology

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Neuropharmacology

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Academic year 2023/2024

Course ID
SVB0057
Teacher
Simona Federica Spampinato
Degree course
Cellular and Molecular Biology
Year
2nd year
Teaching period
To be defined
Type
Distinctive
Credits/Recognition
4
Course disciplinary sector (SSD)
BIO/14 - pharmacology
Delivery
Formal authority
Language
English
Attendance
Optional
Type of examination
Interview
Prerequisites
Students wishing to attend the course of Neuropharmacology should have a good knowledge of General Pharmacology
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Sommario del corso

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Course objectives

This teaching contributes to the learning objectives included in the Fundamental Area of the Master in Cellular and Molecular Biology - Biologia Cellulare e Molecolare, providing knowledge and critical thinking. In particular the course is focused on the knowledge of the treatment of  most relevant neuro and psychiatric disorders. Integrating their knowledge on neurophysiology and  pathology, students will be  able to better understand the pharmacological interventions applyed in neurological disorders.

Students will be given the necessary information to have

  • advanced knowledge on the principal pharmacological approches to treat central nervous system disorders
  • critical analysis skills to understand both preclincal and clinical pharmacological approaches 
  • the ability to understand the scientific literature improving their knowledge as well as their research skills 
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Results of learning outcomes

On completion of this subject students shall be able to

  • Understand and have a strong knowledge on  the main neurotransmitters and receptors present at the CNS level and how to modulate their activity in pathological conditions
  • Extending and applying knowledge on drugs used to treat major classes of brain and mind disorders
  • Research skills to characterize drug action
  • Critically evaluate scientific publications regarding drugs involved in the treatment of neuropsychiatric disorders

 

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Program

1. Introduction to Neuropharmacology
2. Neurotransmitters and Receptor systems in the brain
3. Psychiatric disorders and drugs used to treat them                                                            4. Neurodegenerative disorders and drugs used to treat them
5. Sleep disorders and their treatment
6. Chronic pain and its treatment
7. Addiction and its mechanisms

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Course delivery

The course, delivered in presence consists, of 16 meetings. Each lecture will be followed by homework consisting of multiple-choice questions to train the Student learning. In association to frontal teaching, during which all the topics covered by program will be addressed, the critical reading of scientific articles will be proposed to the class, to deepen specific topics dealt during the previous meetings. The reading of the texts could be done  during the lesson, together with the teacher, or individually and then discussed collectively in the classroom. These discussion in the classroom will be useful to increase practical understanding and to develop a critical vision on the topics studied. Finally, a Neuropharmacology Forum will be open to post questions and/or doubts about the topics covered during the Neuropharmacology Course to increase the interaction between Students and Teacher and among Students.

All lectures will be delivered in presence, subject to updates on the measures adopted by UniTo which can be found on the University portal under "Provisions for those who study and work at UniTo" (see https://en.unito.it/studying-unito)

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Learning assessment methods

The exam will consist of an oral examination.

Brief article presentation (optional): students might give a short presentation before the end of the course based on Neuropharmacology articles selected through a biobliographic search activity. This presentation may provide additional points to the score of the final exam.

 

Exams will take place in presence, subject to updates on the measures adopted by UniTo which can be found on the University portal under "Provisions for those who study and work at UniTo" (see https://en.unito.it/studying-unito)
 
Academic conduct: The penalty for course-related dishonesty (ei. cheating on exams, plagiarism, etc) will be a failure for the entire course.

 

Suggested readings and bibliography

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The teaching materials used for the class lectures will be made available to registered students on the Moodle platform.

Reference Books:

Goodman & Gilman's "The pharmacological basis of therapeutics" Mc Graw Hill Ed.

Katzung "Basic & Clinical Pharmacology" Mc Graw Hill Ed.

Nestler, Hyman & Malenka's "Molecular Neuropharmacology" McGraw Hill Ed.

Stahl "Stahl's essential psychopharmacology" Cambridge Ed

Rang & Dale "Pharmacology" Elsevier Ed.

Francesco Clemente & Guido Fumagalli "General and Molecular Pharmacology" Wiley Ed.



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