Seminar
Published: Thursday, July 8, 2021 by Paola Costelli
5th Epigenetics&Metabolism Webinar on July 15th at 16:00h CET by Dr. Sara Sdelci (Centre for Genomic Regulation, Barcelona), who will give the talk: "Decoding chromatin metabolism in cancer”.
Speaker: Dr. Sara Sdelci, Centre for Genomic Regulation, Barcelona, Spain
Date: July 15th, 2021
Time: 16:00 CET
Talk Title: Decoding chromatin metabolism in cancer
Location: On Zoom (Meeting ID: 831 3757 1311; Passcode: 45950270). Free registration Link: https://us02web.zoom.us/
Abstract: The central role of metabolic rewiring during cancer progression is undeniable, but its direct impact on chromatin functions has been poorly investigated. We recently described that enzymes of central metabolism can localize on chromatin in cancer cells. The scope of our research is to dissect the role of enzymatic activities on chromatin, with a particular focus on cancer. To achieve that, we perform quantitative mass spectrometry and compare the presence of metabolic enzymes in cancer and healthy cells of different tissues. The chromatin-association of particular metabolic entities in specific cancer subtypes may open up the possibility of targeting enzyme localization as a novel and precise anticancer strategy.