Cellular and Molecular Biology

Wednesday 8/11/23 h. 2:00 pm - Hybrid Seminar*
Fernando De Castro, Cajal Institute, Spanish National Research Council, Madrid, Spain
Spontaneous remyelination: hot challenge for Multiple Sclerosis and the gate to go beyond

Spontaneous remyelination has been underestimated to date when treating patients with multiple sclerosis. The first results of a clinical trial that opened the door to this major challenge for Neurology were published around this time, 6 years ago. However, many attempts have failed to go further, basically due to weaknesses in the design of preclinical studies that have fueled false hopes. Our group has specialized in improving these preclinical studies and in exploring new compounds that can be incorporated in the future into the therapeutic arsenal with which to treat multiple sclerosis in combination with immunomodulators available in the clinic. We will show some of these cellular and molecular mechanisms, with special focus on small molecules and aptamers.
Host: Alessandro Vercelli | webex link

* Remember that the seminar room has a limited capacity (25 people) and this limit must be respected (people in excess will not be accepted). The responsibility for enforcing this limit will be up to the host person.